BEGIN:VCALENDAR VERSION:2.0 PRODID:-//CERN//INDICO//EN BEGIN:VEVENT SUMMARY:Neutron research\, Contr. talk 4 - Detection of water in cement mo rtar at room temperature and during freezing DTSTART;VALUE=DATE-TIME:20210510T130000Z DTEND;VALUE=DATE-TIME:20210510T132000Z DTSTAMP;VALUE=DATE-TIME:20260528T084013Z UID:indico-contribution-170-1070@lindico453.srv.lu.se DESCRIPTION:Speakers: Katja Frid (Malmö University)\nWater is present in most of the degradation mechanisms that concrete is exposed to. When these mechanisms are studied experimentally to build models\, it is very import ant that the moisture content in the material is controlled and correct. T he aim for the experiment was to study the water and pore distribution in air-entrained cement mortar with varying moisture preconditioning using du al-modality neutron and x-ray tomography. Furthermore\, in-situ freeze-tha w cycling of cement mortar was performed to visualize the evolution of the water distribution in the pores.\nThe test was divided into two parts. In the first part different moisture pre- conditionings was studied in four samples : (1) Dried at 40C\, (2) Capillary saturated\,\n(3) cured moist ure sealed (4) Vacuum saturated. The samples had a diameter of 10 mm and a height of 10 mm and were moisture sealed during the measurements. A voxel size of 7 μm was used for the neutron imaging and 19.5 μm for the x-ray imaging. Analysis found that it was possible to detect water in the large r pores. It was also found that even after vacuum saturation not all pores were filled.\n\nIn part two\, an in-house built freezing device was used to study the evolving water distribution during freeze-thaw cycling. The d evice was based upon a Peltier element and circulation of a cooling fluid to reach temperatures well below 0C. A vacuum saturated cement mortar s ample (outer diameter 10 mm\, height 10 mm) with water on the top surface was subjected to three freeze-thaw cycles. The sample was imaged at each f rozen/thawed state but due to time limitations\, a full dual-modality data set was only acquired before and at the first freezing as well as at and a fter the third freezing (in total four complete data sets). During the fre ezing\, the temperature was lowered to approximately -13C measured in t he sample and held constant during the imaging. A voxel size of 7 μm was used for the neutron imaging and 19.5 μm for the x-ray imaging.\n\nThe pr eliminary analysis of the sample during freeze-thaw cycling shows some sma ll changes in greyscale value in the cement matrix during temperature cycl ing which can be used to understand the filling of the pore structure due to freezing/thawing. We also found and small changes in relative water con tent of partially filled air voids. This can be used to understand the pro tective role of air voids.\nThis technique is very promising for further v erification of different parts of the mechanism of frost deterioration in concrete. Something that the frost community has longed for!\n\nhttps://li ndico453.srv.lu.se/event/214/contributions/1070/ LOCATION: URL:https://lindico453.srv.lu.se/event/214/contributions/1070/ END:VEVENT BEGIN:VEVENT SUMMARY:Neutron research\, Contr. talk 2 - Sucrose versus trehalose as pos sible preservatives for proteins DTSTART;VALUE=DATE-TIME:20210510T122000Z DTEND;VALUE=DATE-TIME:20210510T124000Z DTSTAMP;VALUE=DATE-TIME:20260528T084013Z UID:indico-contribution-170-1068@lindico453.srv.lu.se DESCRIPTION:Speakers: Inna Ermilova ()\nSucrose and trehalose are well-kno wn industrial preservatives for various purposes: they are widely used in cosmetics\, food conservation and pharmaceutical industry [1\,2]. For inst ance\, sucrose is a stabilizing compound of covid-19 vaccine produced by P fizer [3]. In this work with the help of atomistic molecular dynamics simu lations sucrose and trehalose were considered as agents for preservation o f two model-proteins (myoglobin and Aβ(1-42) peptide) at three different water contents. Results of calculations of self-intermediate scattering fu nctions demonstrated that systems containing sugars with the smaller amoun t of water needed more than 100 ns\, while similar systems without sugars could be relaxed in at around 60-80 ns. Trehalose was the best stabilizing agent in all studied cases which could be a consequence of a slower dynam ics of this sugar.\n\n[1] Olsson\, Christoffer\, Samuel Genheden\, Victori a García Sakai\, and Jan Swenson. "Mechanism of trehalose-induced protei n stabilization from neutron scattering and modeling." The Journal of Phys ical Chemistry B 123\, no. 17 (2019): 3679-3687.\n[2] Starciuc\, Tatiana\, Benjamin Malfait\, Florence Danede\, Laurent Paccou\, Yannick Guinet\, Na talia T. Correia\, and Alain Hedoux. "Trehalose or Sucrose: Which of the T wo Should be Used for Stabilizing Proteins in the Solid State? A Dilemma I nvestigated by In Situ Micro-Raman and Dielectric Relaxation Spectroscopie s During and After Freeze-Drying." Journal of pharmaceutical sciences 109\ , no. 1 (2020): 496-504.\n[3] Vogel\, Annette B.\, Isis Kanevsky\, Ye Che\ , Kena A. Swanson\, Alexander Muik\, Mathias Vormehr\, Lena M. Kranz et al . "BNT162b vaccines protect rhesus macaques from SARS-CoV-2." Nature (2021 ): 1-7.\n\nhttps://lindico453.srv.lu.se/event/214/contributions/1068/ LOCATION: URL:https://lindico453.srv.lu.se/event/214/contributions/1068/ END:VEVENT BEGIN:VEVENT SUMMARY:Neutron research\, Contr. talk 1 - Residual stress and heat treatm ent studies of additively manufactured stainless steel by neutron imaging and diffraction DTSTART;VALUE=DATE-TIME:20210510T120000Z DTEND;VALUE=DATE-TIME:20210510T122000Z DTSTAMP;VALUE=DATE-TIME:20260528T084013Z UID:indico-contribution-170-1067@lindico453.srv.lu.se DESCRIPTION:Speakers: Tuerdi Maimaitiyili (Swerim AB)\nOne of the biggest limitations of parts made by Selective Laser Melting (SLM) is the high ten sile residual stresses that accumulate in the near-surface region. They ar e known to have a detrimental effect on mechanical properties and can even cause SLM process failure. Therefore\, it is always needing to be applied additional heat treatment operations to relieve stress or shock peening t o convert the tensile stress to the compressive stresses. Without the know ledge of residual stress in the material\, it is not possible to estimate the service life or ensure the integrity of machine parts. Among various e xperimental techniques\, only neutron and high-energy synchrotron X-ray te chniques allow us to accurately measure the deep internal stress in large metallic samples with all stress components nondestructively. In this talk \, we will discuss how neutron techniques are important for additive manuf acturing or metallic materials research in general and present some of our residual stress characterization work performed on SLM build stainless st eel which utilized both standard neutron diffraction and neutron Bragg edg e imaging to investigate the effect of Hot Isostatic Pressing (HIP) temper ature and heat treatment to the residual stress.\n\nAcknowledgment: The pr oject is funded by Vinnova (2019-05304).\n\nhttps://lindico453.srv.lu.se/e vent/214/contributions/1067/ LOCATION: URL:https://lindico453.srv.lu.se/event/214/contributions/1067/ END:VEVENT BEGIN:VEVENT SUMMARY:Neutron research\, Contr. talk 5 - The solution structure of the p entameric ligand-gated ion channel GLIC probed by small-angle neutron scat tering DTSTART;VALUE=DATE-TIME:20210510T132000Z DTEND;VALUE=DATE-TIME:20210510T134000Z DTSTAMP;VALUE=DATE-TIME:20260528T084013Z UID:indico-contribution-170-1071@lindico453.srv.lu.se DESCRIPTION:Speakers: Marie Lycksell (Stockholm University)\nPentameric li gand-gated ion channels undergo subtle conformational cycling to control e lectrochemical signal transduction in many kingdoms of life. Several cryst al structures have now been reported in this family\, but the functional r elevance of such models remains unclear. We used small-angle neutron scatt ering (SANS) to probe ambient solution-phase properties of the pH-gated ba cterial ion channel GLIC under resting and activating conditions. Data col lection was optimized by inline paused-flow size-exclusion chromatography\ , and exchanging into deuterated detergent to hide the micelle contributio n. Resting-state GLIC was the best-fit crystal structure to SANS curves\, with no evidence for divergent mechanisms. Moreover\, enhanced-sampling mo lecular dynamics simulations enabled differential modeling in resting vers us activating conditions\, with the latter corresponding to an intermediat e ensemble of both the extracellular and transmembrane domains. This work demonstrates state-dependent changes in a pentameric ion channel by SANS\, an increasingly applicable method for macromolecular characterization as neutron source brilliance increases and inline SEC-SANS set-ups become inc reasingly accessible.\n\nhttps://lindico453.srv.lu.se/event/214/contributi ons/1071/ LOCATION: URL:https://lindico453.srv.lu.se/event/214/contributions/1071/ END:VEVENT BEGIN:VEVENT SUMMARY:Neutron research\, Contr. talk 3 - Na-Ion Dynamics in the Solid So lution Ca1-xNaxCr2O4 Studied by Muon Spin Rotation and Neutron Diffraction DTSTART;VALUE=DATE-TIME:20210510T124000Z DTEND;VALUE=DATE-TIME:20210510T130000Z DTSTAMP;VALUE=DATE-TIME:20260528T084013Z UID:indico-contribution-170-1069@lindico453.srv.lu.se DESCRIPTION:Speakers: Elisabetta Nocerino (KTH)\nStrongly anisotropic and especially one-dimensional or quasi-one-dimensional (Q1D) compounds are ga ining increasing attention from the scientific community. In the field of condensed matter physics\, 1D magnets have been extensively studied for fu ndamental research purposes\, but recently also for their potential use in spintronic applications. In the area of energy materials\, the anisotropi c materials are important for the development of all-solid-state devices w here a better control of the ion-diffusion is highly desirable\nIn this wo rk we present the results of a systematic series of measurements carried o ut by muon spin rotation/relaxation (mu+SR) and neutron diffraction (ND) o n the Q1D solid solution Ca1-xNaxCr2O4. This study was aimed at investigat ing the Na-ion dynamics connected to the Q1D diffusion channels in presenc e of defects\, introduced by the Ca doping. The ion diffusion mechanism ha s been identified as interstitialcy and the diffusion coefficient for each member of the solid solution has been estimated.\n\nhttps://lindico453.sr v.lu.se/event/214/contributions/1069/ LOCATION: URL:https://lindico453.srv.lu.se/event/214/contributions/1069/ END:VEVENT END:VCALENDAR