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SUMMARY:Serial X – Simple Solutions for Serial Synchrotron Crystallograp
 hy
DTSTART;VALUE=DATE-TIME:20250922T164000Z
DTEND;VALUE=DATE-TIME:20250922T165000Z
DTSTAMP;VALUE=DATE-TIME:20260525T163029Z
UID:indico-contribution-1844@lindico453.srv.lu.se
DESCRIPTION:Speakers: Yanyan Chen (Serial X AB)\nSerial X aims to expand o
 f the use of serial crystallography across the academic and industrial lif
 e-science community by introducing low cost\, flexible and easy to use sol
 utions to the problem of sample delivery in serial crystallography experim
 ents at synchrotron radiation facilities. These solutions were invented in
  ProtonPump\, the ERC Advanced Grant awarded to Richard Neutze\, which app
 lies time-resolved serial crystallography to observe structural changes in
  the enzyme cytochrome c oxidase. Serial crystallography is going through 
 a period of rapid development and the number of scientific users of this m
 ethod has the potential to grow by up-to two orders of magnitude. This pot
 ential will never be realized if the current lack of standardization in sa
 mple delivery continues\, which is prohibitively expensive and is often un
 reliable. Serial-X will solve this problem by developing and bringing to m
 arket standardized\, low-cost\, flexible and easy-to-use solutions for sam
 ple delivery in serial crystallography studies at synchrotron radiation so
 urces. With the support of ERC proof-of-concept grant to Richad Neutze\, S
 erial X has developed low-cost products supporting both flow cell1 and fix
 ed target2 approaches to serial crystallography that are mounted upon stan
 dard magnets used at all conventional macromolecular X-ray crystallography
  synchrotron-based beamlines. This will remove the greatest obstacle curre
 ntly preventing scientists from using serial crystallography for their own
  research or for structure based drug-design within a pharmaceutical drug 
 discovery context.\n\n\nAuthors: Yanyan Chen\, Swagatha Ghosh\, Gisela Br
 ändén\, Richard Neutze\n\nhttps://lindico453.srv.lu.se/event/583/contrib
 utions/1844/
LOCATION:LINXS at The Loop
URL:https://lindico453.srv.lu.se/event/583/contributions/1844/
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